Looking at the ultrasonic nano preparation device in front of him, Zhao Heng couldn't help but feel a moment of daze. Just two months ago, he was a rather miserable bottom-tier hospital equipment operator, but now, he is actually in one of the top laboratories in the country and even the world, preparing carbon nanotubes, a high-tech material that appeared only in sci-fi films or novels a decade ago, all by himself.
Carbon nanotubes are allotropes of carbon nano-structures, with length and diameter 1,000,000 times or even more than carbon nano-structures. The excellent physical and chemical properties of carbon nanotubes endow these cylindrical carbon molecules with new capabilities in many applications of nanotechnology, especially their unique surface area, stiffness, strength, and elasticity, making carbon nanotubes a hot topic in pharmaceutical research.
The preparation of carbon nanotubes is still not very perfected. The primary methods of carbon nanotube preparation are arc discharge, laser ablation, and chemical vapor deposition, but the preparation process conditions of these methods are relatively difficult to control, resulting in relatively low quality and yield.
Therefore, under the leadership of Professor Li Hongwei, a brand-new carbon nanotube preparation method was researched and explored, which is the ultrasonic nano preparation device, the silver-white instrument in front of Zhao Heng.
This instrument looks like an ordinary machine tool in size but is worth at least fifty million; indeed, it is a priceless device, not to mention that this device was independently developed by the research team led by Professor Li Hongwei. Globally, the carbon nanotubes it prepares are top-notch in both quality and quantity.
From this, it is clear that Professor Li Hongwei has given Zhao Heng the right to enter here alone and operate this device independently, which is a great show of trust.
As a medical student who graduated from a medical university, Zhao Heng found it originally challenging to start with the cutting-edge technology of carbon nanotube preparation. However, thanks to the system, he previously acquired the corresponding technology from Professor Li Hongwei.
Here, it is necessary to talk about the principle of this ultrasonic nano preparation device. Using ultrasound to prepare carbon nanotubes involves applying ultrasound in a liquid until the ultrasound is strong enough to produce clusters of bubbles in the liquid. Each bubble becomes a hotspot, all subjected to strong ultrasonic action.
During the sparse and compressive phases of ultrasound, bubbles grow, shrink, regrow, and reshrink, oscillating periodically until they finally burst at high speed.
Throughout the periodic oscillation and bursting process, temperatures as high as 2760℃ and pressures approximately 5.05 x 10^8, accompanied by intense shockwaves and micro-jets up to 400km/h, are generated. This micro-jet forms an extremely intense mechanical stirring effect between the interfaces, which can break through the limitations of the laminar boundary layer, enhancing the chemical reaction process and transport process between interfaces, thereby promoting the deposition of decomposed carbon atoms on catalyst particles, eventually forming carbon nanotubes.
Although the process of preparing carbon nanotubes seems simple to describe, the actual situation is not that straightforward.
Let's not even talk about anything else. Just the reaction vessel in front of Zhao Heng, which can accommodate high-temperature and high-pressure reactions, isn't something that can be manufactured casually.
The device in front of Zhao Heng was made thanks to Professor Li Hongwei contacting an engineering academician and entrusting this academician to lead his professional team to prepare it.
Thus, every step of scientific research is incredibly challenging and requires many conditions to be met.
A research field being stagnant for years is all too common in the realm of scientific research.
But now, Zhao Heng can be said to stand on the shoulders of giants. The preparation and application of this nanotube are not merely the achievements of Professor Li Hongwei alone.
Professor Li Hongwei had previously told Zhao Heng that, to a certain extent, his research project was inherited from his teacher, an old academician.
In some major scientific research fields, it may require the efforts of not just one generation, but several generations, to possibly break through a certain bottleneck and turn some theoretical concepts into practical applications.
The process of preparing carbon nanotubes is automatic; Zhao Heng only needs to adjust the parameters and activate the machine, and carbon nanotubes can be automatically generated in the reactor.
The size of carbon nanotubes allows them to directly pass through cell membranes into the nucleus without causing harm to the cells, and the cells do not consider them to be harmful invaders. Once inside the cell, carbon nanotubes directly inject the molecules they carry into the nucleus, thus completing the transport and precise release of drugs.
The next step is to load the drug onto the carbon nanotube.
To realize drug transport, two aspects of work must be relied upon: one is the loading of drug molecules into the carbon nanotube, and the other is the transmission of drug molecules inside the carbon nanotube and their release at the target location. This process is also known as molecular pumping.
In this regard, Professor Li Hongwei and his team have matured their research, and the drug Mitifoxin is also available in the Yanjing University's biological laboratory drug library. Before entering the laboratory, Zhao Heng had already retrieved it.
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